Dipeptidyl peptidase-4

Dipeptidyl peptidase-4 (DPP4 or DPPIV), also known as adenosine deaminase complexing protein 2 or CD26 (cluster of differentiation 26) is a protein

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by SVSK Kasina · 2023 · Cited by 93 — Dipeptidyl peptidase 4 (DPP-4) inhibitors are a group of antihyperglycemic medications used to manage type 2 diabetes mellitus.

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Dipeptidyl peptidase 4 (DPP4) is a widely expressed, serine protease which regulates the bioactivity of many peptides through cleavage and inactivation ...

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Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation.

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dipeptidyl peptidase IV (DPP IV) might play role(s) in amyloid formation and is upregulated in Alzheimer's brain neurons and occurs in multiple ...

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by K Dungan · Cited by 12 — Outline · - Efficacy as monotherapy or combination therapy · - Efficacy in chronic kidney disease · Hypoglycemia and body weight ...

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by CF Deacon · 2019 · Cited by 462 — DPP-4 has been proposed to play a role in linking obesity and the pathogenesis of T2DM by functioning as a local mediator of inflammation and insulin ...

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DPP-4 inhibitors are a class of prescription medicines that are used with diet and exercise to control high blood sugar in adults with type ...

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The IUPHAR/BPS Guide to Pharmacology. dipeptidyl peptidase 4 - S9: Prolyl oligopeptidase. Detailed annotation on the structure, function, physiology, ...

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by CF Deacon · 2020 · Cited by 390 — Overall, DPP4i have a favourable therapeutic profile and are safe and effective in the majority of patients with type 2 diabetes mellitus.

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