About von Willebrand Disease

Von Willebrand factor (VWF) is a blood glycoprotein that promotes primary hemostasis, specifically, platelet adhesion. It is deficient and/or defective in ...

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by GA Cortes · 2023 · Cited by 21 — Von Willebrand factor (vWF) is a glycoprotein crucial to primary hemostasis through platelet and subendothelial collagen adhesion and the intrinsic coagulation ...

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Von Willebrand disease (VWD) is a blood disorder in which the blood does not clot properly. Blood contains many proteins that help the blood clot when needed.

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The usual cause of von Willebrand disease is a changed gene passed through families. Conditions that happen in this way are called inherited.

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The VWF gene provides instructions for making a blood clotting protein called von Willebrand factor. Learn about this gene and related ...

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In von Willebrand disease, genetic mutations affect your body's ability to make normal von Willebrand factor. Factors are proteins that help your blood to clot.

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by JE Sadler · 1998 · Cited by 1947 — Von Willebrand factor (VWF) is a blood glycoprotein that is required for normal hemostasis, and deficiency of VWF, or von Willebrand disease (VWD), is the most ...

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by PJ LENTING · 2012 · Cited by 331 — von Willebrand factor (VWF) is a protein best known from its critical role in hemostasis. Indeed, any dysfunction of VWF is associated with a severe ...

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by TA Springer · 2014 · Cited by 566 — von Willebrand factor (VWF), with help from our circulatory system and platelets, harnesses the same forces to form a hemostatic plug.

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Von Willebrand factor recombinant injection is used to treat and control serious bleeding episodes in patients with a bleeding problem called von Willebrand ...

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